CK, CK-MB and myoglobin, respec tively.7,11 A percent relative index was also computed by dividing the total CK activity into the CK-MB concentration. 早期實驗室應用酵素活性測定法(Measurements of Enzyme Activity)偵測CK 及CK- MB activity,急診室醫師可利用CK-MBactivity Relative Index(﹪RI)>6﹪ 14 Sep 2010 A calculation of the CK-MB amount relative to total CK measurements (relative index) has been useful to differentiate the source of CK-MB CK-MB relative index. J Emerg Med. 2003;24(4):361-7. Voermans NC, de Visser M, Wokke JH, Brusse E. Increased CK The diagnostic sensitivity of both CK-MB (activity or mass) and the troponins cTnI seemed to be as sensitive as and more specific than the CK-MB index. promise as a relatively cheap and noninvasive risk stratification tool, perhaps both
Creatine Kinase MB/Creatine Kinase Ratio Does this test have other names? Ratio of CK-MB to total CK, cardiac index. What is this test? This test measures the amount of creatine kinase (CK), an enzyme, in your blood. It also measures a certain isoenzyme of CK called CK-MB. This is found mostly in the heart. Relative index = CK-MB / Total CK x 100. What does an increased CK and increased CK-MB with a ratio > 6% indicate? Cardiac damage (MI) What relative index value indicates cardiac damage? > 6%. What is the function of myoglobin? Oxygen binding protein in muscle. When the heart muscle is damaged, the CPK-MB fraction is found in the blood. About the Author. Paula Papp is a freelance writer who has worked as a registered nurse for more than 22 years and holds a Masters degree in business administration from Adelphi University. Papp has published numerous articles and studies related to women's health
16 Aug 2012 Using a combination of troponin T and CK-MB relative index, sensitivity on presentation was increased to 90.6%. The sensitivity was improved The relative index of CK-MB to total CK (CK-MB/CK) can help the clinician assess whether the rise in CK-MB is attributable to a skeletal muscle source The relative index (RI = CKMB mass/CK), for CKMB mass measurements, was calculated. Clinical notes and/or discharge diagnosis for each patient were There is no clear consensus on whether absolute CK-MB or the CK-MB relative index is the preferred test for patients with potential acute coronary syndromes.10 - For CKMB mass measurements, the relative index (RI = CKMB mass/CK) was calculated. The diagnosis of acute myocardial infarction was obtained from
If the value of CK-MB is elevated and the ratio of CK–MB to total CK (relative index) is more than 2.5 - 3, it is likely that the heart was damaged A high CK with a relative index below 2.5 - 3.0 suggests that skeletal muscle and not cardiac muscle was damaged. CK-MB/CK relative index is only useful when there is an elevation of both the total CK and the CK-MB levels. Cardiac troponins. Troponins (T, I, C) are regulatory proteins found in striated and cardiac muscle. There are 3 sub-units of troponin. Troponin I (TnI), Troponin T (TnT), and; Troponin C (TnC). However, the CK-MB relative index had a higher positive predictive value for all three outcomes. Because only patients with chest pain were enrolled in this study, some atypical presentations of
早期實驗室應用酵素活性測定法(Measurements of Enzyme Activity)偵測CK 及CK- MB activity,急診室醫師可利用CK-MBactivity Relative Index(﹪RI)>6﹪ 14 Sep 2010 A calculation of the CK-MB amount relative to total CK measurements (relative index) has been useful to differentiate the source of CK-MB CK-MB relative index. J Emerg Med. 2003;24(4):361-7. Voermans NC, de Visser M, Wokke JH, Brusse E. Increased CK The diagnostic sensitivity of both CK-MB (activity or mass) and the troponins cTnI seemed to be as sensitive as and more specific than the CK-MB index. promise as a relatively cheap and noninvasive risk stratification tool, perhaps both The relative index calculated by the ratio of CK-MB (mass) to total CK can assist in differentiating false-positive elevations of CK-MB arising from skeletal muscle. A ratio of less than 3 is consistent with a skeletal muscle source, while ratios greater than 5 are indicative of a cardiac source. If CK-MB is elevated and the ratio of CK-MB to total CK (relative index) is more than 2.5-3, then it is likely that the heart was damaged. A high CK with a relative index below this value suggests that skeletal muscles were damaged. If CK-MB is elevated and the ratio of CK-MB to total CK (relative index) is more than 2.5-3, then it is likely that the heart was damaged. A high CK with a relative index below this value suggests that skeletal muscles were damaged.